{"id":25630,"date":"2025-07-28T11:42:52","date_gmt":"2025-07-28T09:42:52","guid":{"rendered":"https:\/\/www.vsl.nl\/?p=25630"},"modified":"2025-09-10T17:31:49","modified_gmt":"2025-09-10T15:31:49","slug":"characterization-of-nanoparticles-using-machine-learning-2","status":"publish","type":"post","link":"https:\/\/www.vsl.nl\/en\/working-at-vsl\/internship\/characterization-of-nanoparticles-using-machine-learning-2\/","title":{"rendered":"Characterization of nanoparticles using machine learning"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_section full_width=&#8221;stretch_row&#8221; content_placement=&#8221;middle&#8221; css=&#8221;.vc_custom_1753687809550{background-image: url(https:\/\/www.vsl.nl\/wp-content\/uploads\/2025\/07\/header-internship.jpg?id=25632) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}&#8221; el_class=&#8221;main_header gradient_header dg-position-realtive&#8221;][vc_row equal_height=&#8221;yes&#8221; content_placement=&#8221;middle&#8221; el_class=&#8221;dg-header&#8211;small&#8221;][vc_column width=&#8221;2\/3&#8243; el_class=&#8221;dg-padding-none full_width_responsive&#8221;][vc_column_text css=&#8221;.vc_custom_1753686997714{margin-bottom: 0px !important;padding-bottom: 0px !important;}&#8221; el_class=&#8221;text-white&#8221;]<\/p>\n<h1>Internship: Characterization of nanoparticles using machine learning<\/h1>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/3&#8243;][\/vc_column][\/vc_row][\/vc_section][vc_section el_class=&#8221;dg-padding-mid&#8221;][vc_row el_class=&#8221;dg-padding-small-top&#8221;][vc_column width=&#8221;2\/3&#8243; el_class=&#8221;dg-padding-none full_width_responsive&#8221;][vc_column_text css=&#8221;.vc_custom_1753688016169{padding-right: 10% !important;}&#8221;]<\/p>\n<p class=\"header_subtext\">Internship<\/p>\n<h2>Characterization of nanoparticles using machine learning<\/h2>\n<p>Nanoparticles are of increasing importance for health care (nanomedicine), semiconductor industry (quantum dots) and the environment (nanoplastics). One way to measure nanoparticles is by using flow cytometry, a method where a laser beam illuminates a particle and the light scattering of the particle is monitored. Particle properties are\u00a0 generally determined using Mie theory which, given the properties of the particle (e.g., radius and refractive index), determines how the scattering pattern will be when the particle is hit by a laser of given properties (e.g., wavelength).<\/p>\n<p>In our measurement setup the challenge is to solve the inverse problem, i.e., given the scattering pattern determine the radius and refractive index of the particle that generated it. The inverse problem is ill-posed and one way to solve it is by using machine learning (ML). However, the performance of the ML approach needs to be benchmarked against other traditional methods.<\/p>\n<p>As part of this internship the candidate will<\/p>\n<ul>\n<li aria-level=\"1\">Perform a literature review on available methods (excluding ML) to solve the inverse problem in Mie theory<\/li>\n<li aria-level=\"1\">Select and implement at least one approach identified in the literature review<\/li>\n<li aria-level=\"1\">Fine tune and benchmark an in-house ML model designed to solve the inverse problem<\/li>\n<li aria-level=\"1\">Evaluate the uncertainties associated with the predictions of the approach from the literature and with the predictions of the ML model<\/li>\n<\/ul>\n<p>The work will be carried out at VSL (Delft) within the Data Science and Modelling group and in collaboration with the Length group. The ideal candidate has a good understanding of inverse problems, numerical analysis, and ML. Programming experience (preferably in Python) is required.<\/p>\n<p><strong>Internship term:<\/strong> Six months<br \/>\n<strong>Location:<\/strong> Hybrid with at least 2 days per week at our office in Delft<br \/>\n<strong>Allowance:<\/strong> A monthly allowance of \u20ac 615,- (gross) is applicable[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/3&#8243; css=&#8221;.vc_custom_1757518302473{margin-top: 0px !important;margin-right: 0px !important;margin-bottom: 0px !important;margin-left: 0px !important;padding-top: 0px !important;padding-right: 0px !important;padding-left: 0px !important;}&#8221; el_class=&#8221;tablet_expert full_width_responsive&#8221;]<div class=\"templatera_shortcode\"><section class=\"vc_section\"><div class=\"vc_row wpb_row vc_row-fluid full_width_responsive\"><div class=\"dg-specialist--inner dg-padding--none-inner wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner vc_custom_1757057705883\"><div class=\"wpb_wrapper\">\n\t<div  class=\"wpb_single_image wpb_content_element vc_align_left  vc_custom_1765283005843  dg-expert--image\">\n\t\t\n\t\t<figure class=\"wpb_wrapper vc_figure\">\n\t\t\t<div class=\"vc_single_image-wrapper   vc_box_border_grey\"><img decoding=\"async\" width=\"500\" height=\"333\" data-src=\"https:\/\/www.vsl.nl\/wp-content\/uploads\/2022\/11\/Lydia-2025-web.jpg\" class=\"vc_single_image-img attachment-full lazyload\" alt=\"\" title=\"Lydia-2025-web\" data-srcset=\"https:\/\/www.vsl.nl\/wp-content\/uploads\/2022\/11\/Lydia-2025-web.jpg 500w, https:\/\/www.vsl.nl\/wp-content\/uploads\/2022\/11\/Lydia-2025-web-300x200.jpg 300w\" data-sizes=\"(max-width: 500px) 100vw, 500px\"  data-dt-location=\"https:\/\/www.vsl.nl\/en\/lydia-2025-web\/\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 500px; --smush-placeholder-aspect-ratio: 500\/333;\" \/><\/div>\n\t\t<\/figure>\n\t<\/div>\n<div class=\"vc_row wpb_row vc_inner vc_row-fluid dg-padding--square vc_custom_1757057909078 vc_row-o-equal-height vc_row-o-content-middle vc_row-flex\"><div class=\"dg-padding--none-inner dg-expert--inner-content wpb_column vc_column_container vc_col-sm-12\"><div class=\"vc_column-inner vc_custom_1757058090823\"><div class=\"wpb_wrapper\">\n\t<div class=\"wpb_text_column wpb_content_element  vc_custom_1757511576211 dg-expert--content-header\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<h3><strong>Want to know more about interning at VSL?<\/strong><\/h3>\n<p>Our experts are ready to help.<\/p>\n\n\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"wpb_text_column wpb_content_element  vc_custom_1757062953648 sector_specialist\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<p><b>Lydia de Koning<\/b><br \/>\nHR adviseur<\/p>\n\n\t\t<\/div>\n\t<\/div>\n\n\t<div class=\"wpb_raw_code wpb_raw_html wpb_content_element vc_custom_1757062977677\" >\n\t\t<div class=\"wpb_wrapper\">\n\t\t\t<i class=\"far fa-envelope green_icon\"><\/i> <a class=\"custom_link_specialist\" href=\"mailto:ldekoning@vsl.nl\"> ldekoning@vsl.nl<\/a>\n\t\t<\/div>\n\t<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section>\r\n<\/div>[\/vc_column][\/vc_row][vc_row el_class=&#8221;dg-padding-small-top&#8221;][vc_column width=&#8221;5\/6&#8243; el_class=&#8221;dg-padding-none full_width_responsive&#8221;][vc_column_text css=&#8221;&#8221; el_class=&#8221;vacancy_checklist&#8221;]<\/p>\n<h2>About VSL<\/h2>\n<p>VSL is the National Metrology Institute of the Netherlands. We develop and manage national measurement standards on behalf of the Dutch government. We ensure that these are among the best in the world and are internationally accepted. We also provide customer calibrations, customized projects, reference materials, interlaboratory comparisons and training.<\/p>\n<p>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/6&#8243; css=&#8221;.vc_custom_1658406431703{margin-top: 0px !important;margin-right: 0px !important;margin-bottom: 0px !important;margin-left: 0px !important;padding-top: 0px !important;padding-right: 0px !important;padding-left: 0px !important;}&#8221; el_class=&#8221;full_width_responsive&#8221;][\/vc_column][\/vc_row][vc_row el_class=&#8221;dg-padding-small-top&#8221;][vc_column width=&#8221;5\/6&#8243; el_class=&#8221;dg-padding-none full_width_responsive&#8221;][vc_column_text css=&#8221;&#8221; el_class=&#8221;vacancy_checklist&#8221;]If you are interested in ML, image processing and metrology, and would like to know more about R&amp;D projects, this internship is a perfect opportunity. For further questions about the project, please do not hesitate to contact Federica Gugole (<a href=\"mailto:fgugole@vsl.nl\">fgugole@vsl.nl<\/a>) scientist in the Data Science and Modelling group. If you are interested and will apply, please send your CV and motivation letter to Lydia de Koning (<a href=\"mailto:ldekoning@vsl.nl\">ldekoning@vsl.nl<\/a>).[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/6&#8243; css=&#8221;.vc_custom_1658406431703{margin-top: 0px !important;margin-right: 0px !important;margin-bottom: 0px !important;margin-left: 0px !important;padding-top: 0px !important;padding-right: 0px !important;padding-left: 0px !important;}&#8221; el_class=&#8221;full_width_responsive&#8221;][\/vc_column][\/vc_row][\/vc_section]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>This internship applies ML to solve inverse Mie theory problems for nanoparticle characterization.<\/p>\n","protected":false},"author":2,"featured_media":25637,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[67],"tags":[],"class_list":["post-25630","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-internship","category-67","description-off"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - 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